Which two systems work together to facilitate waste removal from cellular metabolism?

The correct answer highlights the collaboration between the cardiac and respiratory systems in facilitating the removal of waste from cellular metabolism. Cellular metabolism produces carbon dioxide and other metabolic waste products that need to be efficiently eliminated from the body. The respiratory system plays a crucial role by taking in oxygen and expelling carbon dioxide during the process of breathing.

When blood travels through the cardiovascular system, it carries carbon dioxide produced by cells to the lungs. Here, carbon dioxide is exchanged for oxygen, enabling its removal from the bloodstream during exhalation. The heart, as part of the cardiac system, pumps this oxygenated blood throughout the body and helps maintain the circulation necessary for efficient waste removal.

In this context, other systems like the muscular and endocrine systems, or the digestive and respiratory systems, do not play direct primary roles in waste elimination from metabolism. Although the nervous system and muscles might assist in movement and activities like breathing, they are not primarily responsible for the waste removal process in the way that the cardiac and respiratory systems are.